PRME insider buying – Prime Medicine, Inc.

12 insider purchases since 2016 worth $55.8M by 9 different insiders. Last 12 months: 0 purchases, $0. Most recent filing: 2025-08-05.

Small company Public float $239M (latest 10-K, SEC). Share prices of small companies usually swing much more than those of large ones, in both directions, and are easier to move with little trading.

Where insiders bought and sold PRME – last 5 yearsCEO / officers Directors Funds & 10% owners Sales

Same time range as the chart above - each mark sits under the week of the trade. Circles = purchases (height = price paid, size = amount), red triangles = open-market sales of $50k+. Prices as reported, not adjusted for later stock splits.

Purchases are open-market buys (SEC Form 4, code "P") - insiders paying with their own money. Sales are open-market sales (code "S") of $50,000 or more; many sales are pre-planned (Rule 10b5-1) or made for taxes and diversification. Each row links to the original filing.

Bought, sold, still holding?

InsiderBoughtFirst / last buySold since 2016Holds now*Status
ARCH Venture Partners X, L.P.
10% Owner
$20.0M
1× · 3,200,000 sh
2024-02-15
2024-02-15
–15,456,594 shares
as of 2024-02-20
Holds - never sold
NELSEN ROBERT
Director
$13.6M
1× · 800,000 sh
2022-10-24
2022-10-24
–18,502,974 shares
as of 2025-08-01
Holds - never sold
GILLIS STEVEN
10% Owner
$10.0M
1× · 3,030,300 sh
2025-08-01
2025-08-01
–18,486,894 shares
as of 2025-08-01
Holds - never sold
Cahill Thomas
Director
$6.8M
1× · 400,000 sh
2022-10-24
2022-10-24
–5,305,679 shares
as of 2022-10-26
Holds - never sold
Alphabet Inc.
10% Owner
$5.0M
1× · 1,500,000 sh
2025-08-01
2025-08-01
3× · $3.4M
last 2023-06-15
3,262,440 shares
as of 2025-08-05
Holds (sold earlier)
Liu David R.
10% Owner
$163,170
4× · 84,000 sh
2025-06-11
2025-06-30
–20,240,945 shares
as of 2025-07-01
Holds - never sold
Reine Allan
CEO
$147,500
1× · 125,000 sh
2025-05-21
2025-05-21
–125,000 shares
as of 2025-05-22
Holds - never sold
LEE ANN L.
Officer
$113,000
1× · 100,000 sh
2025-05-21
2025-05-21
–100,000 shares
as of 2025-05-22
Holds - never sold
Brudnick Richard
Officer
$23,800
1× · 20,000 sh
2025-05-20
2025-05-20
–20,000 shares
as of 2025-05-22
Holds - never sold

* Shares held after the insider's most recent SEC filing for this company (all share classes, direct and indirect). If an insider stops filing, later changes are not known.

Insider buying and selling by year

YearPurchasesBoughtBuyersSalesSold
20259$15.4M6––
20241$20.0M1––
20230––15$20.0M
20222$20.4M2––

Insider purchases

FiledInsiderRoleSharesAvg priceValueHoldingsFiling
2025-08-05Alphabet Inc.10% Owner1,500,000$3.30$5.0M+85.1%SEC
2025-08-01GILLIS STEVEN10% Owner3,030,300$3.30$10.0M+94.7%SEC
2025-07-01Liu David R.10% Owner21,000$2.52$52,920+0.1%SEC
2025-06-23Liu David R.10% Owner21,000$2.16$45,360+0.1%SEC
2025-06-16Liu David R.10% Owner21,000$1.49$31,290+0.1%SEC
2025-06-12Liu David R.10% Owner21,000$1.60$33,600+0.1%SEC
2025-05-22Reine AllanCEO125,000$1.18$147,500SEC
2025-05-22LEE ANN L.Officer100,000$1.13$113,000SEC
2025-05-22Brudnick RichardOfficer20,000$1.19$23,800SEC
2024-02-20ARCH Venture Partners X, L.P.10% Owner3,200,000$6.25$20.0MSEC
2022-10-26NELSEN ROBERTDirector800,000$17.00$13.6M+15.0%SEC
2022-10-26Cahill ThomasDirector400,000$17.00$6.8M+8.2%SEC

Insider sales

FiledInsiderRoleSharesAvg priceValueTypeFiling
2023-06-22GV 2021 GP, L.P.10% Owner56,408$15.03$847,794Pre-planned (10b5-1)SEC
2023-06-20Alphabet Inc.10% Owner73,191$14.93$1.1MPre-planned (10b5-1)SEC
2023-06-15GV 2021 GP, L.P.10% Owner57,060$15.00$855,788Pre-planned (10b5-1)SEC
2023-06-13GV 2019 GP, L.L.C.10% Owner31,703$14.73$467,075Pre-planned (10b5-1)SEC
2023-06-09GV 2021 GP, L.P.10% Owner20,000$16.62$332,500Pre-planned (10b5-1)SEC
2023-06-07GV 2021 GP, L.P.10% Owner52,409$16.88$884,822Pre-planned (10b5-1)SEC
2023-06-02GV 2021 GP, L.L.C.10% Owner61,856$14.16$876,179Pre-planned (10b5-1)SEC
2023-05-31GV 2019 GP, L.L.C.10% Owner29,407$13.70$402,876Pre-planned (10b5-1)SEC
2023-05-26Alphabet Inc.10% Owner31,061$13.45$417,808Pre-planned (10b5-1)SEC
2023-05-24Alphabet Inc.10% Owner131,861$14.33$1.9MPre-planned (10b5-1)SEC
2023-05-22GV 2021 GP, L.P.10% Owner90,310$13.63$1.2MPre-planned (10b5-1)SEC
2023-05-18GV 2021, L.P.10% Owner65,649$12.63$829,221Pre-planned (10b5-1)SEC
2023-05-16GV 2019 GP, L.L.C.10% Owner185,242$12.74$2.4MPre-planned (10b5-1)SEC
2023-05-12GV 2019, L.P.10% Owner114,023$13.82$1.6MPre-planned (10b5-1)SEC
2023-05-10GV 2021 GP, L.P.10% Owner422,010$14.09$5.9MPre-planned (10b5-1)SEC

Compiled automatically from public SEC filings. Not investment advice. Get every new insider purchase in the daily report.

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