PRLD insider buying – Prelude Therapeutics Inc
23 insider purchases since 2016 worth $72.5M by 10 different insiders. Last 12 months: 1 purchases, $12.5M. Most recent filing: 2026-04-23.
Small company Public float $14M (latest 10-K, SEC). Share prices of small companies usually swing much more than those of large ones, in both directions, and are easier to move with little trading.
Same time range as the chart above - each mark sits under the week of the trade. Circles = purchases (height = price paid, size = amount), red triangles = open-market sales of $50k+. Prices as reported, not adjusted for later stock splits. 5 older purchases (before the 5-year window) are listed in the table below.
Purchases are open-market buys (SEC Form 4, code "P") - insiders paying with their own money. Sales are open-market sales (code "S") of $50,000 or more; many sales are pre-planned (Rule 10b5-1) or made for taxes and diversification. Each row links to the original filing.
Bought, sold, still holding?
| Insider | Bought | First / last buy | Sold since 2016 | Holds now* | Status |
|---|---|---|---|---|---|
| Baker Bros. Advisors (GP) LLC Director | $30.0M 1× · 1,578,947 sh | 2020-09-29 2020-09-29 | – | 870,873 shares as of 2020-09-30 | Holds - never sold |
| ORBIMED ADVISORS LLC Director | $23.5M 1× · 1,236,800 sh | 2020-09-25 2020-09-25 | – | 526,300 shares as of 2020-09-29 | Holds - never sold |
| OrbiMed Genesis GP LLC Director | $12.5M 1× · 2,815,315 sh | 2026-04-21 2026-04-21 | – | 1,126,126 shares as of 2026-04-23 | Holds - never sold |
| Bonita David P Director | $5.0M 1× · 869,565 sh | 2023-05-22 2023-05-22 | – | 1,126,126 shares as of 2026-04-23 | Holds - never sold |
| Vaddi Krishna CEO | $856,021 8× · 979,953 sh | 2022-12-20 2025-03-25 | – | 2,565,504 shares as of 2025-03-27 | Holds - never sold |
| Combs Andrew Officer | $268,616 4× · 172,075 sh | 2020-09-29 2025-03-25 | – | 480,123 shares as of 2025-03-27 | Holds - never sold |
| Dier Mardi Director | $190,000 1× · 10,000 sh | 2020-09-29 2020-09-29 | – | 10,000 shares as of 2020-09-29 | Holds - never sold |
| Chardonnet Laurent CFO | $117,400 3× · 25,000 sh | 2022-06-01 2023-05-23 | – | 42,165 shares as of 2023-05-25 | Holds - never sold |
| Pierce Christopher Officer | $71,250 1× · 3,750 sh | 2020-09-29 2020-09-29 | 2× · $841,276 last 2021-09-02 | 3,750 shares as of 2021-09-07 | Sold part |
| Lim Bryant David CFO | $35,686 2× · 27,400 sh | 2023-05-24 2024-12-19 | – | 27,400 shares as of 2024-12-20 | Holds - never sold |
* Shares held after the insider's most recent SEC filing for this company (all share classes, direct and indirect). If an insider stops filing, later changes are not known.
Insider buying and selling by year
| Year | Purchases | Bought | Buyers | Sales | Sold |
|---|---|---|---|---|---|
| 2026 | 1 | $12.5M | 1 | – | – |
| 2025 | 6 | $660,708 | 2 | – | – |
| 2024 | 3 | $207,616 | 3 | – | – |
| 2023 | 4 | $5.1M | 4 | 1 | $81,274 |
| 2022 | 3 | $188,334 | 2 | – | – |
| 2021 | 1 | $94,880 | 1 | 23 | $10.2M |
| 2020 | 5 | $53.8M | 5 | – | – |
Insider purchases
| Filed | Insider | Role | Shares | Avg price | Value | Holdings | Filing |
|---|---|---|---|---|---|---|---|
| 2026-04-23 | OrbiMed Genesis GP LLC | Director | 2,815,315 | $4.44 | $12.5M | +31.3% | SEC |
| 2025-03-27 | Vaddi Krishna | CEO | 675,000 | $0.69 | $465,750 | +51.0% | SEC |
| 2025-03-27 | Combs Andrew | Officer | 100,000 | $0.69 | $69,000 | +26.3% | SEC |
| 2025-03-24 | Vaddi Krishna | CEO | 20,416 | $0.73 | $14,904 | +1.6% | SEC |
| 2025-03-18 | Vaddi Krishna | CEO | 39,105 | $0.75 | $29,329 | +3.1% | SEC |
| 2025-03-14 | Vaddi Krishna | CEO | 97,500 | $0.72 | $69,725 | +8.4% | SEC |
| 2025-01-02 | Vaddi Krishna | CEO | 10,000 | $1.20 | $12,000 | +7.8% | SEC |
| 2024-12-26 | Combs Andrew | Officer | 63,075 | $1.36 | $85,736 | +20.1% | SEC |
| 2024-12-20 | Lim Bryant David | CFO | 25,000 | $0.91 | $22,750 | +1041.7% | SEC |
| 2024-12-20 | Vaddi Krishna | CEO | 106,888 | $0.93 | $99,130 | +10.1% | SEC |
| 2023-05-25 | Lim Bryant David | Officer | 2,400 | $5.39 | $12,936 | SEC | |
| 2023-05-25 | Vaddi Krishna | CEO | 11,856 | $5.63 | $66,749 | +1.1% | SEC |
| 2023-05-25 | Chardonnet Laurent | CFO | 5,000 | $5.50 | $27,500 | +13.5% | SEC |
| 2023-05-24 | Bonita David P | Director | 869,565 | $5.75 | $5.0M | +9.4% | SEC |
| 2022-12-21 | Vaddi Krishna | CEO | 19,188 | $5.13 | $98,434 | +18.9% | SEC |
| 2022-12-12 | Chardonnet Laurent | CFO | 10,000 | $4.76 | $47,600 | +38.7% | SEC |
| 2022-06-01 | Chardonnet Laurent | CFO | 10,000 | $4.23 | $42,300 | +69.0% | SEC |
| 2021-12-15 | Combs Andrew | Officer | 8,000 | $11.86 | $94,880 | +3.1% | SEC |
| 2020-09-30 | Baker Bros. Advisors (GP) LLC | Director | 1,578,947 | $19.00 | $30.0M | +20.6% | SEC |
| 2020-09-29 | Pierce Christopher | Officer | 3,750 | $19.00 | $71,250 | SEC | |
| 2020-09-29 | Dier Mardi | Director | 10,000 | $19.00 | $190,000 | SEC | |
| 2020-09-29 | Combs Andrew | Officer | 1,000 | $19.00 | $19,000 | +0.4% | SEC |
| 2020-09-29 | ORBIMED ADVISORS LLC | Director | 1,236,800 | $19.00 | $23.5M | SEC |
Insider sales
| Filed | Insider | Role | Shares | Avg price | Value | Type | Filing |
|---|---|---|---|---|---|---|---|
| 2023-04-06 | Huang Jane | CEO | 13,280 | $6.12 | $81,274 | Sale | SEC |
| 2021-12-17 | Morosini Deborah | Officer | 28,751 | $13.00 | $373,763 | Sale | SEC |
| 2021-11-18 | Morosini Deborah | Officer | 28,751 | $15.88 | $456,502 | Sale | SEC |
| 2021-10-06 | Mauro David J | Officer | 15,000 | $30.96 | $464,335 | Sale | SEC |
| 2021-09-09 | Mauro David J | Officer | 15,000 | $36.69 | $550,275 | Sale | SEC |
| 2021-09-07 | Pierce Christopher | Officer | 17,000 | $41.68 | $708,520 | Sale | SEC |
| 2021-08-30 | Scherle Peggy | Officer | 7,714 | $35.75 | $275,769 | Sale | SEC |
| 2021-08-27 | Piper Brian | CFO | 8,333 | $33.34 | $277,825 | Sale | SEC |
| 2021-08-17 | Scherle Peggy | Officer | 2,286 | $35.07 | $80,170 | Sale | SEC |
| 2021-08-09 | Mauro David J | Officer | 15,000 | $31.09 | $466,410 | Sale | SEC |
| 2021-07-29 | Scherle Peggy | Officer | 20,000 | $35.47 | $709,435 | Sale | SEC |
| 2021-07-08 | Mauro David J | Officer | 15,000 | $27.48 | $412,136 | Sale | SEC |
| 2021-06-09 | Mauro David J | Officer | 15,000 | $32.44 | $486,619 | Sale | SEC |
| 2021-05-27 | Piper Brian | CFO | 8,333 | $34.27 | $285,551 | Sale | SEC |
| 2021-05-11 | Scherle Peggy | Officer | 10,000 | $40.82 | $408,212 | Sale | SEC |
Showing the latest 15 of 24 sales of $50,000+ since 2016.
Compiled automatically from public SEC filings. Not investment advice. Get every new insider purchase in the daily report.
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