OPK insider buying – Opko Health, Inc.
584 insider purchases since 2016 worth $142.0M by 13 different insiders. Last 12 months: 5 purchases, $3.0M. Most recent filing: 2026-03-20.
Mid company Public float $540M (latest 10-K, SEC).
Where insiders bought and sold OPK – last 5 yearsCEO / officers Directors Funds & 10% owners Sales
Same time range as the chart above - each mark sits under the week of the trade. Circles = purchases (height = price paid, size = amount), red triangles = open-market sales of $50k+. Prices as reported, not adjusted for later stock splits. 486 older purchases (before the 5-year window) are listed in the table below.
Purchases are open-market buys (SEC Form 4, code "P") - insiders paying with their own money. Sales are open-market sales (code "S") of $50,000 or more; many sales are pre-planned (Rule 10b5-1) or made for taxes and diversification. Each row links to the original filing.
Bought, sold, still holding?
| Insider | Bought | First / last buy | Sold since 2016 | Holds now* | Status |
|---|---|---|---|---|---|
| FROST PHILLIP MD ET AL CEO | $70.0M 270× · 24,170,741 sh | 2015-12-31 2025-10-31 | – | 248,082,576 shares as of 2025-10-31 | Holds - never sold |
| Frost Gamma Investments Trust CEO | $50.5M 193× · 22,441,336 sh | 2016-01-06 2025-11-21 | – | 250,402,576 shares as of 2025-11-21 | Holds - never sold |
| Frost Nevada Investments Trust CEO | $15.9M 71× · 5,898,351 sh | 2018-01-22 2019-07-12 | – | 53,205,390 shares as of 2019-07-15 | Holds - never sold |
| Nabel Gary J. Officer | $1.9M 4× · 991,900 sh | 2022-05-12 2024-01-08 | – | 1,272,710 shares as of 2024-07-26 | Holds - never sold |
| HSIAO JANE PH D Officer | $1.8M 13× · 939,610 sh | 2012-07-27 2024-01-17 | – | 33,627,284 shares as of 2024-07-26 | Holds - never sold |
| Zerhouni Elias A. CEO | $764,077 2× · 639,900 sh | 2022-05-10 2024-01-05 | – | 20,917,414 shares as of 2024-07-26 | Holds - never sold |
| Fishel Robert Scott Director | $317,025 8× · 115,000 sh | 2018-04-06 2019-05-28 | – | 4,180,728 shares as of 2021-01-26 | Holds - never sold |
| PFENNIGER RICHARD C JR Director | $256,240 5× · 155,000 sh | 2019-05-13 2024-01-05 | – | 325,000 shares as of 2024-01-05 | Holds - never sold |
| Rubin Steven D Officer | $207,636 11× · 68,000 sh | 2016-03-30 2023-11-10 | – | 6,571,966 shares as of 2026-07-28 | Holds - never sold |
| Cohen Jon R Officer | $190,500 1× · 50,000 sh | 2021-05-10 2021-05-10 | – | 125,000 shares as of 2021-06-01 | Holds - never sold |
| PAGANELLI JOHN A Director | $85,150 4× · 50,000 sh | 2017-06-01 2026-03-20 | – | 403,515 shares as of 2026-03-20 | Holds - never sold |
| LERNER RICHARD A Director | $63,138 1× · 10,000 sh | 2017-06-05 2017-06-05 | – | 243,881 shares as of 2018-05-15 | Holds - never sold |
| KRASNO RICHARD M Director | $29,700 1× · 30,000 sh | 2024-01-29 2024-01-29 | – | 103,333 shares as of 2024-01-29 | Holds - never sold |
* Shares held after the insider's most recent SEC filing for this company (all share classes, direct and indirect). If an insider stops filing, later changes are not known.
Insider buying and selling by year
| Year | Purchases | Bought | Buyers | Sales | Sold |
|---|---|---|---|---|---|
| 2026 | 1 | $11,400 | 1 | – | – |
| 2025 | 15 | $6.4M | 2 | – | – |
| 2024 | 27 | $11.9M | 8 | – | – |
| 2023 | 11 | $5.4M | 6 | – | – |
| 2022 | 40 | $15.3M | 4 | – | – |
| 2021 | 11 | $7.4M | 3 | – | – |
| 2020 | 37 | $12.2M | 3 | – | – |
| 2019 | 89 | $20.3M | 8 | – | – |
| 2018 | 89 | $15.4M | 4 | – | – |
| 2017 | 126 | $29.5M | 6 | 1 | $911,708 |
| 2016 | 138 | $18.2M | 4 | 1 | $368,510 |
Insider purchases
| Filed | Insider | Role | Shares | Avg price | Value | Holdings | Filing |
|---|---|---|---|---|---|---|---|
| 2026-03-20 | PAGANELLI JOHN A | Director | 10,000 | $1.14 | $11,400 | +2.6% | SEC |
| 2025-11-21 | Frost Gamma Investments Trust | CEO | 580,000 | $1.33 | $770,219 | +0.3% | SEC |
| 2025-11-20 | Frost Gamma Investments Trust | CEO | 580,000 | $1.33 | $772,381 | +0.3% | SEC |
| 2025-11-19 | Frost Gamma Investments Trust | CEO | 580,000 | $1.31 | $760,572 | +0.3% | SEC |
| 2025-11-18 | Frost Gamma Investments Trust | CEO | 533,300 | $1.28 | $680,795 | +0.2% | SEC |
| 2025-10-31 | FROST PHILLIP MD ET AL | CEO | 150,000 | $1.42 | $213,000 | +0.1% | SEC |
| 2025-08-08 | FROST PHILLIP MD ET AL | CEO | 675,000 | $1.32 | $891,000 | +0.3% | SEC |
| 2025-04-10 | FROST PHILLIP MD ET AL | CEO | 125,000 | $1.36 | $170,000 | +0.1% | SEC |
| 2025-04-08 | Frost Gamma Investments Trust | CEO | 125,000 | $1.48 | $185,000 | +0.1% | SEC |
| 2025-04-01 | FROST PHILLIP MD ET AL | CEO | 100,000 | $1.65 | $165,000 | +0.0% | SEC |
| 2025-03-28 | Frost Gamma Investments Trust | CEO | 150,000 | $1.70 | $255,000 | +0.1% | SEC |
| 2025-03-17 | Frost Gamma Investments Trust | CEO | 200,000 | $1.74 | $348,000 | +0.1% | SEC |
| 2025-02-28 | Frost Gamma Investments Trust | CEO | 67,434 | $1.71 | $115,312 | +0.0% | SEC |
| 2025-01-28 | Frost Gamma Investments Trust | CEO | 47,537 | $1.47 | $69,879 | +0.0% | SEC |
| 2025-01-17 | Frost Gamma Investments Trust | CEO | 150,000 | $1.47 | $220,500 | +0.1% | SEC |
| 2025-01-15 | FROST PHILLIP MD ET AL | CEO | 500,000 | $1.48 | $740,000 | +0.2% | SEC |
| 2024-12-13 | Frost Gamma Investments Trust | CEO | 125,000 | $1.60 | $200,000 | +0.1% | SEC |
| 2024-12-11 | Frost Gamma Investments Trust | CEO | 500,000 | $1.56 | $780,000 | +0.2% | SEC |
| 2024-11-29 | Frost Gamma Investments Trust | CEO | 199,072 | $1.53 | $304,580 | +0.1% | SEC |
| 2024-11-22 | Frost Gamma Investments Trust | CEO | 100,000 | $1.59 | $159,000 | +0.0% | SEC |
| 2024-11-14 | FROST PHILLIP MD ET AL | CEO | 100,000 | $1.62 | $162,000 | +0.0% | SEC |
| 2024-11-08 | FROST PHILLIP MD ET AL | CEO | 280,183 | $1.50 | $420,274 | +0.1% | SEC |
| 2024-05-23 | Frost Gamma Investments Trust | CEO | 100,000 | $1.27 | $127,000 | +0.0% | SEC |
| 2024-05-17 | Frost Gamma Investments Trust | CEO | 163,997 | $1.29 | $211,556 | +0.1% | SEC |
| 2024-03-18 | Frost Gamma Investments Trust | CEO | 500,000 | $0.87 | $435,000 | +0.2% | SEC |
| 2024-03-14 | FROST PHILLIP MD ET AL | CEO | 500,000 | $0.89 | $445,000 | +0.2% | SEC |
| 2024-03-13 | Frost Gamma Investments Trust | CEO | 500,000 | $0.93 | $465,000 | +0.2% | SEC |
| 2024-03-12 | Frost Gamma Investments Trust | CEO | 600,000 | $0.93 | $558,000 | +0.3% | SEC |
| 2024-02-28 | FROST PHILLIP MD ET AL | CEO | 500,000 | $0.99 | $495,000 | +0.2% | SEC |
| 2024-02-21 | FROST PHILLIP MD ET AL | CEO | 1,000,000 | $0.99 | $990,000 | +0.5% | SEC |
| 2024-02-07 | Frost Gamma Investments Trust | CEO | 1,500,000 | $0.98 | $1.5M | +0.7% | SEC |
| 2024-01-29 | KRASNO RICHARD M | Director | 30,000 | $0.99 | $29,700 | +40.9% | SEC |
| 2024-01-19 | Frost Gamma Investments Trust | CEO | 500,000 | $0.98 | $490,000 | +0.2% | SEC |
| 2024-01-18 | FROST PHILLIP MD ET AL | CEO | 400,000 | $0.97 | $388,000 | +0.2% | SEC |
| 2024-01-17 | HSIAO JANE PH D | Officer | 150,000 | $0.95 | $142,500 | +0.5% | SEC |
| 2024-01-16 | Frost Gamma Investments Trust | CEO | 1,000,000 | $0.95 | $950,000 | +0.5% | SEC |
| 2024-01-11 | Frost Gamma Investments Trust | CEO | 511,531 | $0.94 | $480,839 | +0.3% | SEC |
| 2024-01-10 | Nabel Gary J. | Officer | 216,184 | $0.93 | $201,046 | +159.8% | SEC |
| 2024-01-08 | HSIAO JANE PH D | Officer | 150,010 | $0.87 | $130,509 | +0.5% | SEC |
| 2024-01-08 | Frost Gamma Investments Trust | CEO | 1,500,000 | $0.90 | $1.4M | +0.7% | SEC |
Showing the latest 40 of 584 purchases.
Insider sales
| Filed | Insider | Role | Shares | Avg price | Value | Type | Filing |
|---|---|---|---|---|---|---|---|
| 2017-03-15 | Logal Adam | CEO | 112,975 | $8.07 | $911,708 | Sale | SEC |
| 2016-05-17 | BARON ROBERT A | Director | 37,500 | $9.83 | $368,510 | Sale | SEC |
Recent company events (SEC 8-K)
- 2026-11-04 - Quarterly results released (SEC)
Compiled automatically from public SEC filings. Not investment advice. Get every new insider purchase in the daily report.
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